B-vitamins are important for hundreds of biochemical reactions in the body. B vitamin deficiency can lead to fatigue and lethargy, which is why B-complex supplements are excellent energy boosters and anti-stress formulas.
Now, according to a recent study published in the American Journal of Clinical Nutrition, two of these important B-vitamins – vitamins B6 and B12 – could protect older adults from the symptoms of depression.
Kimberly Skarupski, an associate professor at Rush University Medical Center in Chicago, and a team of researchers studied over 3,500 seniors (ages 65+) in the Chicago area and found that “increased intakes of vitamins B6 and B12 were associated with a ‘decreased likelihood of incident depression’. The intakes of the vitamins came from both food and supplements”:
Our results support the hypotheses that high total intakes of vitamins B6 and B12 are protective of depressive symptoms over time in community-residing older adults.
World Health Organization statistics indicate that an estimated 5.8% of men and 9.5% of women world-wide will experience a depressive episode in any given year, making depression one of the most common psychiatric disorder encountered in general medical practice.
So why the link between vitamins B6 and B12 and depression? According to a 2003 European study, there is a “biologically plausible link” between B vitamin intake and depressive symptoms. According to that study’s authors, vitamin B12 may “inhibit the accumulation of the amino acid homocysteine, … which may lead to toxic reactions that enhance depression.”
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